Replacement for SecureCRT/Putty/etc for sysadmins working on large installations. It can send wake-on-lan packets, has support for expect scripts on a connection, RDP and VNC remote desktops, works behind proxies, and and allows you to ignore .ssh/known-hosts key mismatch (If you've ever migrated a server to another IP you'll know what it is ;-) ).
We're using this to operate a 500+ hosts CDN. I hope you enjoy it.