Not the typical question on HN. But just seeing so many people in the Valley aiming to be the next Mark Zuckerberg / Bill Gates. Such a goal comes at a great cost. Not only the amount of work required but you'll probably need to chase high risk opportunities which the vast majority of the time end in failure.
Or do you want something like 37signals? More of a lifestyle company, with 4 day workweeks on the Summer. Jason Fried is influential in many circles.
Or something like patio (kalzumeus.com)... solopreneur. I think I read he works 10 hours a week but stills makes an impact?
Pluses and minuses to each.