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1.

Endometriosis is an interesting disease

a year ago

392 points

2.

The truth behind the 2026 J.P. Morgan Healthcare Conference

5 months ago

326 points

3.

Administering immunotherapy in the morning seems to matter. Why?

a year ago

239 points

4.

A primer on the current state of longevity research

2 years ago

179 points

5.

Mapping the off-target effects of every FDA-approved drug in existence

8 months ago

162 points

6.

The Ballad of TIGIT

a month ago

110 points

7.

A primer on why microbiome research is hard

2 years ago

91 points

8.

A Primer on Molecular Dynamics

a year ago

90 points

9.

RNA structure prediction is hard. How much does that matter?

9 months ago

70 points

10.

A printing press for biological data

2 months ago

67 points

11.

There aren't enough smart people in biology doing something boring

2 years ago

66 points

12.

Why Recursion Pharmaceuticals abandoned cell painting for brightfield imaging

2 years ago

66 points

13.

Will protein design tools solve the snake antivenom shortage?

a year ago

63 points

14.

Creating the largest protein-protein interaction dataset in the world

2 years ago

61 points

15.

The unreasonable effectiveness of plasmid sequencing as a service

2 years ago

48 points

16.

A 2026 look at three bio-ML opinions I had in 2024

5 months ago

28 points

17.

Why computational predictive toxicology is hard

2 years ago

24 points

18.

The optimistic case for protein foundation model companies

8 months ago

18 points

19.

The Origin of Rot

6 months ago

10 points

20.

How to build a cancer vaccine, and whether they will work this time

5 days ago

8 points

21.

Cancer has a surprising amount of detail

8 months ago

7 points

22.

The ML drug discovery startup trying really, really hard to not cheat

6 months ago

7 points

23.

Reasons to be pessimistic (and optimistic) on the future of biosecurity

5 days ago

6 points

24.

How to build a cancer vaccine, and whether they will work this time

14 days ago

6 points

25.

Reasons to be pessimistic (and optimistic) on the future of biosecurity

3 months ago

6 points

26.

We don't know what most microbial genes do. Can genomic language models help?

6 months ago

6 points

27.

How do you make a 250x better vaccine at 1/10 the cost? Develop it in India

a year ago

6 points

28.

Ask not why would you work in biology, but rather: why wouldn't you?

9 months ago

5 points

29.

Curious cases of financial engineering in biotech

2 months ago

5 points

30.

Reasons to be pessimistic (and optimistic) on the future of biosecurity

3 months ago

5 points